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In Graves' disease, the immune system makes an antibody to one part of the cells in the hormone-making gland in the neck, called the thyroid gland. A tiny gland at the base of the brain, called the pituitary gland, makes a hormone that controls the thyroid gland.
Graves’ disease is a lifelong (chronic) autoimmune disease that causes your thyroid to make too much thyroid hormone. It happens because your body makes antibodies to your thyroid gland.
Graves' disease is an autoimmune disorder, in which the body produces antibodies that are specific to a self-protein - the receptor for thyroid-stimulating hormone.
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With Graves’ disease, your immune system attacks your thyroid gland, causing it to make more thyroid hormones than your body needs. As a result, many of your body’s functions speed up.
Graves disease is the prototypical autoimmune cause of hyperthyroidism. It results from circulating thyroid‑stimulating immunoglobulins (TSIs) that bind to and activate the thyroid-stimulating hormone (TSH) receptor on thyroid follicular cells, driving continuous intracellular cyclic adenosine monophosphate (cAMP) signaling. This aberrant stimulation leads to excess production of thyroid ...
Graves disease is the most common cause of hyperthyroidism. It is due to an abnormal immune system response that causes the thyroid gland to produce too much thyroid hormone.
