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Sandifer syndrome is a condition characterized by unusual movements of your child’s head, neck and back. The condition can cause temporary muscle spasms as a reaction to acid reflux.
Sandifer syndrome was first described in 1964 by Austrian neurologist Marcel Kinsbourne in The Lancet. [6][7] Kinsbourne named the syndrome after his mentor, British neurologist Paul Sandifer, who had initially cared for the patients described in Kinsbourne's case reports. [8][9][10]
What is Sandifer syndrome? Sandifer syndrome is a movement disorder characterized by paroxysmal dystonia (i.e., intermittent muscle contractions causing atypical and often painful movements) with severe opisthotonic, or backward, arching of the neck and back.
Sandifer syndrome is caused by genetic mutations, also known as pathogenic variants. Genetic mutations can be hereditary, when parents pass them down to their children, or they may occur randomly when cells are dividing.
Sandifer syndrome | About the Disease | GARD - Genetic and Rare ...
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Learn about the symptoms and treatment of Sandifer syndrome, a condition that causes spasms and acid reflux in children.
Sandifer syndrome is commonly misdiagnosed as seizures or a neurological movement disorder. Symptoms can resemble seizures, infantile spasms, infant torticollis, a muscular condition, and paroxysmal dystonia, a movement disorder that also sees attacks of abnormal posturing.
